![]() See identical proteins and their annotated locations for NP_599022.1 Location: 91 → 185 NR_DBD_ROR DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers ![]() Location: 297 → 536 NR_LBD_ROR_like The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily cd06968 As a result, variant 3 encodes isoform c, whose 91 N-terminal aa differ from the 66 N-terminal aa of isoform a encoded by variant 1. Status: REVIEWED Description Transcript Variant: This variant (3), also called RORalpha3, contains a different 5' sequence as compared to variant 1. See identical proteins and their annotated locations for NP_002934.1 NG_029246.2 RefSeqGene Range 5000.746018 Download GenBank, FASTA, Sequence Viewer (Graphics) This section to the one reported in Genomic regions, Identify version mismatches by comparing the version of the RefSeq in These reference sequences are curated independently of the genomeĪnnotation cycle, so their versions may not match the RefSeq versions in the current These reference sequences exist independently of genome builds. Expression Broad expression in skin (RPKM 15.9), adrenal (RPKM 10.1) and 21 other tissues See more Orthologs mouse all NEW Try the new Gene table Four transcript variants encoding different isoforms have been described for this gene. ![]() ![]() Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. Full Name RAR related orphan receptor A provided by HGNC Primary source HGNC:HGNC:10258 See related Ensembl:ENSG00000069667 MIM:600825 AllianceGenome:HGNC:10258 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as ROR1 ROR2 ROR3 RZRA NR1F1 RORa1 IDDECA RORalpha RZR-ALPHA Summary The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. ![]()
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